Which finding is commonly observed in patients with multiple myeloma?

In patients with multiple myeloma, hypercalcemia is a commonly observed finding due to the increased osteoclastic activity associated with bone lesions. Multiple myeloma leads to the destruction of bone tissue as malignant plasma cells accumulate in the bone marrow, causing the release of calcium into the bloodstream. This condition can result in elevated calcium levels, which may present clinically with symptoms such as fatigue, confusion, constipation, and increased thirst.

The association between multiple myeloma and increased calcium levels is significant, making hypercalcemia a hallmark feature of the disease. It is essential for healthcare providers to monitor calcium levels in these patients, as hypercalcemia can lead to severe complications that require prompt intervention.