Which cells contain Auer rods?

Auer rods are abnormal cytoplasmic inclusions that are typically associated with myeloblasts. These structures are formed from aggregates of granule materials and are an important diagnostic feature in identifying certain types of acute myeloid leukemia (AML). The presence of Auer rods is particularly indicative of acute myeloid leukemia or other myeloproliferative disorders, highlighting the significance of myeloblasts in the hematopoietic system. They serve as a marker for myeloid lineage and help pathologists differentiate myeloid neoplasms from lymphoid neoplasms.

In contrast, monoblasts, bands (immature neutrophils), and erythrocytes do not contain Auer rods. Monoblasts, while also significant in myeloid lineage, do not typically show these inclusions. Bands, being more mature granulocyte precursors, similarly lack Auer rods. Erythrocytes, on the other hand, do not have granules and are not involved in myeloid differentiation, making the presence of Auer rods irrelevant. Therefore, myeloblasts are the only cell type in this context that contains Auer rods and serves as a critical factor in hematological diagnoses.