What is the most common inherited bleeding disorder?

Study for the ASCP Specialist in Hematology (SH) Test. Prepare with multiple choice questions, each providing hints and explanations. Boost your readiness for the exam!

The most common inherited bleeding disorder is von Willebrand disease. This condition results from a deficiency or dysfunction of von Willebrand factor, which plays a critical role in platelet adhesion and aggregation. It is characterized by a range of bleeding symptoms, including easy bruising, prolonged bleeding after injury, and heavy menstrual bleeding.

In contrast to von Willebrand disease, hemophilia A, while a significant inherited bleeding disorder and notable for its association with Factor VIII deficiency, is less prevalent than von Willebrand disease in the general population. Thrombocytopenia refers to a low platelet count and can occur due to various reasons, including inherited conditions, but it is not classified as a single inherited bleeding disorder. DIC is an acquired condition that results in systemic activation of coagulation and is not inherited.

Thus, von Willebrand disease is recognized as the most common inherited bleeding disorder due to its higher prevalence among genetic bleeding disorders.

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